the effect of intrauterine human chorionic gonadotropin injection before embryo transfer on the implantation and pregnancy rate in infertile patients: a randomized clinical trial
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abstract
background: implantation is one of the essential steps for the success of assisted reproductive techniques (art). their success depends on three main factors: embryo quality, endometrial receptivity (er), and synchrony between embryo and endometrium. there are various factors that regulate the complex process of implantation. in this regard, one may refer to human chorionic gonadotropin (hcg) as the most important factor.objective: this study aims to investigate the effect of intrauterine hcg injection before embryo transfer (et) on pregnancy outcome in infertile couples.materials and methods: a total of 159 patients undergone in vitro fertilization/ intracytoplasmic sperm injection (ivf/icsi) with an antagonist protocol were evaluated. patients were divided into three groups (n=53). group 1 received 500 iu of hcg, group 2 received 1000 iu of hcg intrauterine injection before et, and the control group underwent et without hcg preceding intrauterine injection.results: there was no significant difference among the groups. the implantation rates were 18.86%, 13.52%, and 14.37%, chemical pregnancy rates were 34%, 32.1%, and 35.3%, and clinical pregnancy rates were 34%, 32.1%, and 31.4% respectively.conclusion: the pregnancy outcome in ivf/icsi /et cycles cannot be improved through hcg intrauterine injections before et.
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The effect of intrauterine human chorionic gonadotropin injection before embryo transfer on the implantation and pregnancy rate in infertile patients: A randomized clinical trial
BACKGROUND Implantation is one of the essential steps for the success of assisted reproductive techniques (ART). Their success depends on three main factors: embryo quality, endometrial receptivity (ER), and synchrony between embryo and endometrium. There are various factors that regulate the complex process of implantation. In this regard, one may refer to human chorionic gonadotropin (hCG) as...
full textO-32: Effects of Intrauterine Injection of Recombinant Human Chorionic Gonadotropin before Embryo Transfer on Outcome of In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Randomized Clinical Trial
Background: To evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). Materials and Methods: In this randomized placebocontrolled clinical trial, a total number of 182 infertile patients undergoing their first in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) were randomly assigned to receive 250 μg i...
full texteffect of intrauterine injection of human chorionic gonadotropin before embryo transfer on pregnancy rates: a prospective randomized study
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full textintrauterine administration of recombinant human chorionic gonadotropin before embryo transfer on outcome of in vitro fertilization/ intracytoplasmic sperm injection: a randomized clinical trial
background: the direct effect of hcg on the human endometrium was studied several times. objective: the objectives of this study were to evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhcg) before embryo transfer (et). materials and methods: in this randomized placebo-controlled clinical trial, a total number of 182 infertile patients undergoin...
full textIntrauterine administration of recombinant human chorionic gonadotropin before embryo transfer on outcome of in vitro fertilization/ intracytoplasmic sperm injection: A randomized clinical trial
BACKGROUND The direct effect of hCG on the human endometrium was studied several times. OBJECTIVE The objectives of this study were to evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). MATERIALS AND METHODS In this randomized placebo-controlled clinical trial, a total number of 182 infertile patients undergoi...
full textEffect of intrauterine injection of human chorionic gonadotropin before embryo transfer on clinical pregnancy rates from in vitro fertilisation cycles: a prospective study
BACKGROUND The implantation process after embryo transfer depends on the embryo quality and endometrial receptivity. It is estimated that fifty to seventy-five per cent of pregnancies are lost due to a failure of implantation. There is evidence that there is an early secretion of human chorionic gonadotrophin before embryo implantation, and this secretion has been linked to an important functio...
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Journal title:
international journal of reproductive biomedicineجلد ۱۴، شماره ۱۰، صفحات ۶۵۷-۰
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